Progress in Biomedical Optics and Imaging, vol. 6, No. 8 ISSN 1605-7422, p. 444-449

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Studying brain function with near-infrared spectroscopy concurrently with electroencephalography
 Tạp chí Progress in Biomedical Optics and Imaging 2005 ; 6 (8):444-449
 Tác giả   Y. Tong*1, E. J. Rooney2, P. R. Bergethon2, J. M. Martin1, A. Sassaroli1, B. L. Ehrenberg1, Vo Van Toi1, P. Aggarwal3, N. Ambady4, and S. Fantini1
 Nơi thực hiện   1Tufts University, Department of Biomedical Engineering, Medford, MA, 2Tufts New England Medical Center, Department of Neurology, Boston, MA, 3Boston University, Department of Psychology, Boston, MA, 4Tufts University, Department of Psychology, Medford, MA
 Từ khóa   near-infrared spectroscopy,electroencephalography,evoked potentials,brain imaging
  DOI   URL  [ PDF]



Near-infrared spectroscopy (NIRS) has been used for functional brain imaging by employing properly designed source-detector matrices. We demonstrate that by embedding a NIRS source-detector matrix within an electroencephalography (EEG) standard multi-channel cap, we can perform functional brain mapping of hemodynamic response and neuronal response simultaneously. In this study, the P300 endogenous evoked response was generated in human subjects using an auditory odd-ball paradigm while concurrently monitoring the hemodynamic response both spatially and temporally with NIRS. The electrical measurements showed the localization of evoked potential P300, which appeared around 320 ms after the odd-ball stimulus. The NIRS measurements demonstrate a hemodynamic change in the fronto-temporal cortex a few seconds after the appearance of P300.

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